Role of stressful and traumatic life events in obsessive-compulsive disorder

LF Fontenelle; L Cocchi; BJ Harrison; EC Miguel; AR Torres

Journal article

Role of stressful and traumatic life events in obsessive-compulsive disorder

LF Fontenelle, L Cocchi, BJ Harrison, EC Miguel, AR Torres

Neuropsychiatry | FUTURE MEDICINE LTD | Published : 2011

DOI: 10.2217/npy.10.1

Abstract

Whilst genetic factors are thought to contribute to the development of obsessive-compulsive disorder (OCD), the role of environmental factors in OCD is only beginning to be understood. In this article, we review the influence of stress-related factors in OCD. Overall, studies indicate that: patients with OCD frequently report stressful and traumatic life events before illness onset, although these rates do not seem to be significantly different from those described in other disorders; the association between OCD and post-traumatic stress disorder (PTSD) might result from symptom overlap, although cases of patients developing OCD after PTSD and showing obsessive-compulsive symptoms that were ..

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University of Melbourne Researchers

Ben Harrison Author

Related Projects (1)

Specific Brain Networks Related to the Symptoms of Obsessive-Compulsive Disorder

Grants

Awarded by Conselho National de Desenvolvimento Cientifico e Tecnologico, Brazil

Awarded by Endeavour Research Fellowship Postdoctoral Research Award

Awarded by NHMRC, Australia

Awarded by Swiss National Science Foundation

Awarded by Swiss Foundation

Awarded by Swiss National Science Foundation (SNF)

Funding Acknowledgements

LF Fontenelle is supported by a grant from the Conselho National de Desenvolvimento Cientifico e Tecnologico, Brazil (Process number 303846/2008-9) and a Endeavour Research Fellowship Postdoctoral Research Award (Process number ID ERF_PDR_1415_2010). BJ Harrison is supported by a NHMRC Clinical Career Development Award, Australia (I.D. 628509). L Cocchi is supported by the Swiss National Science Foundation (Process PBLAB3-119622) and Swiss Foundation for Fellowships in Biology and Medicine (Process PASMP3_129357/1). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.